1. Anti-infection Metabolic Enzyme/Protease
  2. Parasite Drug Metabolite
  3. Albendazole sulfone

Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.

For research use only. We do not sell to patients.

Albendazole sulfone

Albendazole sulfone Chemical Structure

CAS No. : 75184-71-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Albendazole sulfone:

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1][2].

Cellular Effect
Cell Line Type Value Description References
Huh-7 CC50
< 5 μM
Compound: 8
Cytotoxicity against human HuH7 cells
Cytotoxicity against human HuH7 cells
[PMID: 21531135]
Molecular Weight

297.33

Formula

C12H15N3O4S

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(OC)NC1=NC2=CC=C(S(=O)(CCC)=O)C=C2N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (56.07 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3633 mL 16.8163 mL 33.6327 mL
5 mM 0.6727 mL 3.3633 mL 6.7265 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.16%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3633 mL 16.8163 mL 33.6327 mL 84.0817 mL
5 mM 0.6727 mL 3.3633 mL 6.7265 mL 16.8163 mL
10 mM 0.3363 mL 1.6816 mL 3.3633 mL 8.4082 mL
15 mM 0.2242 mL 1.1211 mL 2.2422 mL 5.6054 mL
20 mM 0.1682 mL 0.8408 mL 1.6816 mL 4.2041 mL
25 mM 0.1345 mL 0.6727 mL 1.3453 mL 3.3633 mL
30 mM 0.1121 mL 0.5605 mL 1.1211 mL 2.8027 mL
40 mM 0.0841 mL 0.4204 mL 0.8408 mL 2.1020 mL
50 mM 0.0673 mL 0.3363 mL 0.6727 mL 1.6816 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Albendazole sulfone
Cat. No.:
HY-W019773
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