Albendazole sulfone
Based on 1 Customer Validation
Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
For research use only. We do not sell to patients.
- Purity: 98.16%
- CAS No.: 75184-71-3
- Formula: C12H15N3O4S
- Molecular Weight:297.33
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Parasite Isoforms
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Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
<5 μM
Compound: 8
|
Cytotoxicity against human HuH7 cells
Cytotoxicity against human HuH7 cells
|
[PMID: 21531135] |
Chemical Information
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CAS No. 75184-71-3
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Appearance Solid
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Molecular Weight 297.33
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Formula C12H15N3O4S
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Color White to light yellow
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SMILES
O=C(OC)NC1=NC2=CC=C(S(=O)(CCC)=O)C=C2N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 16.67 mg/mL (56.07 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (622 KB)
- English - EN (622 KB)
- Français - FR (622 KB)
- Deutsch - DE (622 KB)
- Norwegian - NO (622 KB)
- Español - ES (622 KB)
- Swedish - SV (622 KB)
- Italian - IT (622 KB)
- Korean - KR (622 KB)
- Portuguese - PT (622 KB)
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Handling Instructions (2659 KB)
References
[1]. Ingold K, et, al. Efficacies of albendazole sulfoxide and albendazole sulfone against In vitro-cultivated Echinococcus multilocularis metacestodes. Antimicrob Agents Chemother. 1999 May;43(5):1052-61. [Content Brief]
[2]. Adas G, et, al. Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study). World J Gastroenterol. 2009 Jan 7;15(1):112-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3633 mL | 16.8163 mL | 33.6327 mL | 84.0817 mL |
| 5 mM | 0.6727 mL | 3.3633 mL | 6.7265 mL | 16.8163 mL | |
| 10 mM | 0.3363 mL | 1.6816 mL | 3.3633 mL | 8.4082 mL | |
| 15 mM | 0.2242 mL | 1.1211 mL | 2.2422 mL | 5.6054 mL | |
| 20 mM | 0.1682 mL | 0.8408 mL | 1.6816 mL | 4.2041 mL | |
| 25 mM | 0.1345 mL | 0.6727 mL | 1.3453 mL | 3.3633 mL | |
| 30 mM | 0.1121 mL | 0.5605 mL | 1.1211 mL | 2.8027 mL | |
| 40 mM | 0.0841 mL | 0.4204 mL | 0.8408 mL | 2.1020 mL | |
| 50 mM | 0.0673 mL | 0.3363 mL | 0.6727 mL | 1.6816 mL |