2. TGF-beta/Smad
  3. TGF-β Receptor
  4. ALK5-IN-10

ALK5-IN-10 (Compound 5d) is a TGF-β type I receptor kinase ALK5 inhibitor, with IC50s of 0.007 and 1.98 μM for ALK5 and p38α, respectively. ALK5-IN-10 can be used for the research of cancer.

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ALK5-IN-10

ALK5-IN-10 화학구조

CAS No. : 1352608-94-6

사이즈 가격 재고 수량
1 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
10 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
25 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
50 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
100 mg   견적 받기  
200 mg   견적 받기  
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ALK5-IN-10 Related Antibodies

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제품 설명

ALK5-IN-10 (Compound 5d) is a TGF-β type I receptor kinase ALK5 inhibitor, with IC50s of 0.007 and 1.98 μM for ALK5 and p38α, respectively. ALK5-IN-10 can be used for the research of cancer[1].

Cellular Effect
Cell Line Type Value Description References
Sf9 IC50
0.007 μM
Compound: 12d
Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assay
Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assay
[PMID: 24786585]
분자량

460.33

화학식

C22H18BrN7
CAS No.
SMILES

BrC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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ALK5-IN-10 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALK5-IN-101352608-94-6TGF-β ReceptorTransforming growth factor beta receptorsp38αcancerTGF-βInhibitorinhibitorinhibit

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상품명:
ALK5-IN-10
Cat. No.:
HY-151233
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