1. Epigenetics
  2. Histone Methyltransferase
  3. AMI-408

AMI-408 is a PRMT1 inhibitor. AMI-408 can reduce H4R3me2as level in MLL-GAS7 leukemia cells.

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AMI-408

AMI-408 Chemische Struktur

CAS. Nr. : 78866-14-5

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Beschreibung

AMI-408 is a PRMT1 inhibitor. AMI-408 can reduce H4R3me2as level in MLL-GAS7 leukemia cells[1].

IC50 & Target

PRMT1

 

Molekulargewicht

543.32

Formel

C20H13Cl2N6NaO5S

CAS. Nr.
SMILES

O=S(C1=C(/N=N/C2=CC=C(OC)C=C2)C(O)=C3C=CC(NC4=NC(Cl)=NC(Cl)=N4)=CC3=C1)(O[Na])=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Molaritätsrechner

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Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Art. -Nr.:
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