Amiloride hydrochloride dihydrate (Standard)
Amiloride hydrochloride dihydrate (Standard) is the analytical standard of Amiloride hydrochloride dihydrate. This product is intended for research and analytical applications. Amiloride hydrochloride dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is a blocker of polycystin-2 (PC2; TRPP2) channel.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 17440-83-4
- Formula: C6H13Cl2N7O3
- Molecular Weight:302.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 17440-83-4
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Molecular Weight 302.12
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Formula C6H13Cl2N7O3
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SMILES
O=C(C1=NC(Cl)=C(N)N=C1N)NC(N)=N.[H]Cl.O.O
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Synonyms
MK-870 hydrochloride dihydrate (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Miller RL, et al. Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema. Brain Res. 2015 Mar 19;1601:40-51. [Content Brief]
[2]. Xu LB, et al. Amiloride, a urokinase-type plasminogen activator receptor (uTPA) inhibitor, reduces proteinurea in podocytes. Genet Mol Res. 2015 Aug 14;14(3):9518-29. [Content Brief]
[3]. Giamarchi A, et al. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. 2010 Apr 7;29(7):1176-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Amiloride hydrochloride dihydrate (Standard) Related Classifications
HY-B0285BR Related Classifications
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