Anti-Mouse PD-1 Antibody (RMP1-14), CY7 labeled
Based on 1 Customer Validation
Anti-Mouse PD-1 Antibody (RMP1-14), CY7 labeled, is an Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144) derivative carrying dye CY7 (HY-D0825). Anti-Mouse PD-1 Antibody (RMP1-14) is an anti-mouse PD-1 IgG2a antibody. Anti-Mouse PD-1 Antibody (RMP1-14) can be used for the study of colon carcinoma.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
PD-1
In Vitro
In Vivo
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Animal Model:Mouse CT26.CL25 liver metastasis model[1]
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Dosage:10 mg/kg
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Administration:ip, every 3 days for 3-4 doses
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Result:Failed to significantly change immune cells when used alone.
Increased the M1/M2 ratio, increased the number of mature CD4+ T cells and CD8+ T cells, increased the expression of IFN-γ and TNF-α when used with the combination of CAPOX.
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Animal Model:C57BL/6J mouse models[2]
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Dosage:50-200 μg/mouse
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Administration:intradermal injection, single dose
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Result:Increased the number of spontaneous scratching in mice.
Chemical Information
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Appearance Liquid
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Color Light blue to blue
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SMILES
[Anti-Mouse PD-1 Antibody (RMP1-14), CY7 labeled]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)