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Cat. No.: HY-P87736

CD11c Antibody (YA7421)

CD11c Antibody (YA7421) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to CD11c.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	ELISA ELISA: Enzyme Linked Immunosorbent Assay	IP IP: Immunoprecipitation
Dilution Ratio	1:200-1:1000	1:2000-1:10000	1:200-1:1000	1:5000-1:20000	1:50-1:200

Description

CD11c Antibody (YA7421) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to CD11c.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 145 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 128 kDa

Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG,Kappa

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CD11c is an integrin α-chain protein, belonging to the integrin α subunit family. CD11c usually forms a heterodimer αXβ2 integrin with CD18 (Integrin β2, ITGB2). CD11c is one of the most commonly used dendritic cell (DC) markers in immunological research, but it is not actually expressed specifically by DCs; it is expressed in various myeloid immune cells.
Subcellular Localization

Membrane
Expression

Tissue_specificity:It is mainly expressed in monocytes and granulocytes.
Subunit

Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2
SwissProt ID

P20702