CD368 Antibody (YA4390)
(Synonyms: CLEC4D; MCL; MPCL; CLEC6; CLEC-6; CLECSF8; Dectin-3)CD368 Antibody (YA4390) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD368.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
CD368 Antibody (YA4390) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD368.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 25-30 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 24.7 kDa
Purified recombinant fragment of human CD368 (AA: extra 39-215) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD368 core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q16576 has 2 isomers: Q16576-1: 47820 Da (predicted); Q16576-2: 52314 Da (predicted).
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Subunit
Binds directly to helix 1 of the histone fold of histone H4, a region that is not accessible when H4 is in chromatin (PubMed:18571423, PubMed:9427644).
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SwissProt ID
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Synonyms
CLEC4D; MCL; MPCL; CLEC6; CLEC-6; CLECSF8; Dectin-3
Documentation
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