CD56 Antibody (YA5643)
(Synonyms: antigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule, neural, 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_HUMAN; NCAMC; Neural cell adhesion molecule 1; Neural cell adhesion molecule NCAM; OTTHUMP00000235666)CD56 Antibody (YA5643) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD56.
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P, WB, ICC/IF, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:200-1000 | 1:500-2000 | 1:100-500 | 1:1000-5000 |
Product Details
CD56 Antibody (YA5643) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD56.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 100 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 95 kDa
Synthesized peptide derived from human CD56 AA range: 500-600
Protein G
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD56 is a neural cell adhesion molecule (NCAM1) belonging to the immunoglobulin superfamily (IgSF). In the immune system, CD56 is a hallmark surface molecule of NK cells. CD56 is also expressed in some activated T cells (especially NKT-like cells) and participates in processes such as cell adhesion, immune synapse formation, and regulation of cytotoxic function.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Lipid-anchor, GPI-anchor; Cell membrane; Lipid-anchor, GPI-anchor; Secreted; Secreted
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Isoforms & Post-Translational Modification
CD56 has 6 isomers: P13591-2: 94574 Da (predicted); P13591-1: 93361 Da (predicted); P13591-3: 83770 Da (predicted); P13591-4: 80312 Da (predicted); P13591-5: 73473 Da (predicted); P13591-6: 40760 Da (predicted).
Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans -
Subunit
(Microbial infection) Interacts with rabies virus glycoprotein
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SwissProt ID
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Synonyms
antigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule, neural, 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_HUMAN; NCAMC; Neural cell adhesion molecule 1; Neural cell adhesion molecule NCAM; OTTHUMP00000235666
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