DNA Nucleotidylexotransferase Antibody (YA3630)
(Synonyms: TDT)DNA Nucleotidylexotransferase Antibody (YA3630) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DNA Nucleotidylexotransferase.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, FC, ELISA
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Reactivity :
Human, Rat
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:400 | 1:10000 |
Product Details
DNA Nucleotidylexotransferase Antibody (YA3630) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DNA Nucleotidylexotransferase.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 59 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 59 kDa
Purified recombinant fragment of human DNTT (AA: 52-192) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DNA Nucleotidylexotransferase is a Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
P04053 has 2 isomers: P04053-1: 58536 Da (predicted); P04053-2: 58408 Da (predicted).
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Subunit
Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone. Released from this complex by PCNA. Interacts with TRERF1 (PubMed:16371131)
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SwissProt ID
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Synonyms
TDT
Documentation