Hydroxyl-Histone H2A Antibody (YA3332)
(Synonyms: H2A.1; H2A/c; H2A1; H2AFC:; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM; histone cluster 1; H2ai; Histone H2A type 1; Histone H2A/p)Hydroxyl-Histone H2A Antibody (YA3332) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hydroxyl-Histone H2A.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 |
Product Details
Hydroxyl-Histone H2A Antibody (YA3332) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hydroxyl-Histone H2A.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 14 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 14 kDa
Entrez Gene: 3012 Human ; 317772 Human ; 8335 Human ; 8338 Human ; 319166 Mouse ;
SwissProt: P04908 Human ; P0C0S8 Human ; P20671 Human ; Q16777 Human ; Q6FI13 Human ; Q7L7L0 Human ; Q8IUE6 Human ; Q93077 Human ; Q96KK5 Human ; Q96QV6 Human ; Q99878 Human ; P10812 Mouse ; P22752 Mouse ;
OMIM: 602786 Human
A synthesized peptide derived from human Histone H2A (hydroxyl Y39)
Endogenous
Affinity Purified
Non-conjugated
Hydroxylated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Hydroxyl-Histone H2A core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
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Subcellular Localization
Nucleus; Chromosome
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Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
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SwissProt ID
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Synonyms
H2A.1; H2A/c; H2A1; H2AFC:; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM; histone cluster 1; H2ai; Histone H2A type 1; Histone H2A/p
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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