NCAPD2 Antibody (YA6672)
(Synonyms: 2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; 2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; Condensin antibody; Condensin complex subunit 1 antibody; eg7 antibody; hCAP-D2 antibody; hCAPD2 antibody; KIAA0159 antibody; mKIAA0159 antibody; NCAPD2 antibody; non-SMC condensin I complex, subunit D2 antibody; XCAP D2 homolog antibody; )NCAPD2 Antibody (YA6672) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCAPD2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, IHC-P
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Reactivity :
Human
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:100-1:200 | 1:50-1:200 |
Product Details
NCAPD2 Antibody (YA6672) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCAPD2.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 157 kDa
Recombinant protein within human NCAPD2 aa 51-200/1,401.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
NCAPD2 is a Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size[1][2].
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Subcellular Localization
Nucleus,Cytoplasm,Chromosome
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Subunit
Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG
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SwissProt ID
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Synonyms
2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; 2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; Condensin antibody; Condensin complex subunit 1 antibody; eg7 antibody; hCAP-D2 antibody; hCAPD2 antibody; KIAA0159 antibody; mKIAA0159 antibody; NCAPD2 antibody; non-SMC condensin I complex, subunit D2 antibody; XCAP D2 homolog antibody;
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