NCAPD2 Antibody (YA6672)

Cat. No.: HY-P86979: Data Sheet User Guide for Antibodies
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NCAPD2 Antibody (YA6672) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCAPD2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

NCAPD2 Antibody (YA6672) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCAPD2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 157 kDa

Species Reactivity

Human

SwissProt ID

Q15021

Gene ID

9918 [NCBI]

Immunogen

Recombinant protein within human NCAPD2 aa 51-200/1,401.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:200
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain (PubMed:11136719). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (PubMed:27737959)

Subcellular Localization：Nucleus,Cytoplasm,Chromosome

Subunit：Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG

Synonyms

2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; 2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; Condensin antibody; Condensin complex subunit 1 antibody; eg7 antibody; hCAP-D2 antibody; hCAPD2 antibody; KIAA0159 antibody; mKIAA0159 antibody; NCAPD2 antibody; non-SMC condensin I complex, subunit D2 antibody; XCAP D2 homolog antibody;

Documentation

User Guide for Antibodies (1077 KB)