PDLIM5 Antibody (YA8121)
(Synonyms: ENH; ENH1; L9; LIM)PDLIM5 Antibody (YA8121) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PDLIM5.
-
Host:
Mouse
-
Isotype:
IgG2a
-
Application:
FC
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
|
|---|---|
| Dilution Ratio | 1:100 |
Product Details
PDLIM5 Antibody (YA8121) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PDLIM5.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman, Mouse, Rat
-
Calculated Molecular Weight Predicted band size: 63.8 kDa
Full length human recombinant protein of human PDLIM5 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
-
Appearance
Liquid
-
Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
PDLIM5 may play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Isoforms lacking the LIM domains may negatively modulate the scaffolding activity of isoform 1. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May be required to restrain postsynaptic growth of excitatory synapses. Isoform 1, but not isoform 2, expression favors spine thinning and elongation
-
Subcellular Localization
Postsynaptic density,Presynapse,Postsynapse,Cytoplasm, cytosol
-
Expression
Tissue_Specificity: Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression -
Isoforms & Post-Translational Modification
Q96HC4 has 7 isomers: Q96HC4-1: 63945 Da (predicted); Q96HC4-2: 25930 Da (predicted); Q96HC4-3: 23823 Da (predicted); Q96HC4-4: 53078 Da (predicted); Q96HC4-5: 15116 Da (predicted); Q96HC4-6: 67729 Da (predicted); Q96HC4-7: 52645 Da (predicted).
-
Subunit
Interacts with various PKC isoforms through the LIM domains
-
SwissProt ID
-
Synonyms
ENH; ENH1; L9; LIM
Documentation
Powered by Bioz
