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  5. PPM1B Antibody (YA7883)(PBS only)

PPM1B Antibody (YA7883)(PBS only)

Cat. No.: HY-P88199A
User Guide for Antibodies Technical Support

PPM1B Antibody (YA7883) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PPM1B.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

PPM1B Antibody (YA7883) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PPM1B.
Host

Mouse
Molecular Weight

Predicted band size: 52.5 kDa
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Full length human recombinant protein of human PPM1B produced in HEK293T cell.
Application &
Dilution Ratio
Application Dilution Ratio
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:100-250
FC
FC: Flow Cytometry
1:100
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG2a  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB
Subcellular Localization：Cytoplasm, cytosol,Membrane
Expression：
Tissue_Specificity: Highly expressed in heart and skeletal muscle
Isoforms & Post-Translational Modification：O75688 has 5 isomers: O75688-1: 52643 Da (predicted); O75688-2: 42771 Da (predicted); O75688-3: 20753 Da (predicted); O75688-4: 42086 Da (predicted); O75688-5: 36313 Da (predicted).
Isgylation negatively regulates its activity丨N-myristoylation is essential for the recognition of its substrates for dephosphorylation
Subunit：Monomer (By similarity)
Synonyms
PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX
Documentation
User Guide for Antibodies (1077 KB)

PPM1B Antibody (YA7883)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PPM1B Antibody (YA7883)(PBS only)
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