PRDM5 Antibody (YA4517)
(Synonyms: BCS2; PFM2)PRDM5 Antibody (YA4517) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRDM5.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, ICC/IF, FC, ELISA
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:100-1:500 | 1:200-1:400 | 1:10000 |
Product Details
PRDM5 Antibody (YA4517) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRDM5.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 70-75 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 73 kDa
Purified recombinant fragment of human PRDM5 (AA: 1-100) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PRDM5 is a Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May cause G2/M arrest and apoptosis in cancer cells
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues -
Isoforms & Post-Translational Modification
Q9NQX1 has 4 isomers: Q9NQX1-1: 73090 Da (predicted); Q9NQX1-2: 69862 Da (predicted); Q9NQX1-3: 12874 Da (predicted); Q9NQX1-4: 58124 Da (predicted).
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Subunit
Interacts with EHMT2/G9A, GFI1 and HDAC1
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SwissProt ID
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Synonyms
BCS2; PFM2
Documentation
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