PRMT7 Antibody (YA1734)(PBS only)

Cat. No.: HY-P81989A: Data Sheet User Guide for Antibodies
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PRMT7 Antibody (YA1734) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PRMT7.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PRMT7 Antibody (YA1734) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PRMT7.

Host

Rabbit

Molecular Weight

Predicted band size: 78 kDa;

Observed band size: 78 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9NVM4

Gene ID

54496 [NCBI]

Immunogen

A synthetic peptide of human PRMT7

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo

Subcellular Localization：Cytoplasm, cytosol; Nucleus

Isoforms & Post-Translational Modification：Q9NVM4 has 4 isomers: Q9NVM4-1: 78459 Da (predicted); Q9NVM4-2: 62118 Da (predicted); Q9NVM4-3: 73154 Da (predicted); Q9NVM4-4: 63806 Da (predicted).

Subunit：Homodimer and heterodimer (By similarity). Interacts with CTCFL (By similarity). Interacts with PRMT5 and SNRPD3

Research Field

Epigenetics and Nuclear Signaling

Synonyms

SBIDDS

Documentation

User Guide for Antibodies (1077 KB)