PSMC3 Antibody (YA7897)(PBS only)
(Synonyms: DCIDP; RPT5; TBP1)PSMC3 Antibody (YA7897) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PSMC3.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Dog, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:2000-3000 | 1:50-250 | 1:100-250 | 1:100 |
Product Details
PSMC3 Antibody (YA7897) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PSMC3.
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Host Mouse
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Species ReactivityHuman, Dog, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 49.2 kDa
Full length human recombinant protein of human PSMC3 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PSMC3 component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides
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Subcellular Localization
Cytoplasm,Nucleus
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Isoforms & Post-Translational Modification
P17980: 439 amino acids, molecular weight 49204 Da.
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Subunit
Component of the 19S proteasome regulatory particle complex
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SwissProt ID
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Synonyms
DCIDP; RPT5; TBP1
Documentation
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