RASA1 Antibody (YA7218)
(Synonyms: GAP, RASA, RASA1, Ras GTPase-activating protein 1, GTPase-activating protein, RasGAP, Ras p21 protein activator, p120GAP)
Based on 1 Customer Validation
RASA1 Antibody (YA7218) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASA1.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, IHC-F, IF-Tissue, FC
-
Reactivity :
Human, Rat, Mouse
-
Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
IHC-F
IHC-F: Immunohistochemistry-Frozen
|
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
|
FC
FC: Flow Cytometry
|
|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:100-500 | 1:100-500 | 1:50-100 |
Product Details
RASA1 Antibody (YA7218) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASA1.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman, Rat, Mouse
-
Observed Molecular WeightObserved band size: 135 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 116 kDa
A synthesized peptide derived from human RASA1: 250-300.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
RASA1 is an Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1
-
Subcellular Localization
Cytoplasm
-
Expression
Tissue_Specificity: In placental villi, detected only in the trophoblast layer (cytotrophoblast and syncytiotrophoblast). Not detected in stromal, endothelial or Hofbauer cells (at protein level) -
Isoforms & Post-Translational Modification
P20936 has four isomers: P20936-1: 116403 Da (predicted); P20936-2: 100398 Da (predicted); P20936-3: 58037 Da (predicted); P20936-4: 101546 Da (predicted).
The N-terminus is blocked丨Phosphorylated by SRC and LCK -
Subunit
Interacts with SQSTM1
-
SwissProt ID
-
Synonyms
GAP, RASA, RASA1, Ras GTPase-activating protein 1, GTPase-activating protein, RasGAP, Ras p21 protein activator, p120GAP
Documentation
Powered by Bioz
