RASA1 Antibody (YA7218)

Cat. No.: HY-P87534: Ficha de datos User Guide for Antibodies
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RASA1 Antibody (YA7218) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASA1.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

RASA1 Antibody (YA7218) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RASA1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Peso molecular

Predicted band size: 116 kDa;

Observed band size: 140 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P20936

Immunogen

A synthesized peptide derived from human RASA1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-200
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-200
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:100-200

Sensitivity	Endogenous	Pureza	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1

Subcellular Localization：Cytoplasm

Expression：
Tissue_Specificity: In placental villi, detected only in the trophoblast layer (cytotrophoblast and syncytiotrophoblast). Not detected in stromal, endothelial or Hofbauer cells (at protein level)

Isoforms & Post-Translational Modification：P20936 has four isomers: P20936-1: 116403 Da (predicted); P20936-2: 100398 Da (predicted); P20936-3: 58037 Da (predicted); P20936-4: 101546 Da (predicted).
The N-terminus is blocked丨Phosphorylated by SRC and LCK

Subunit：Interacts with SQSTM1

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/lovo-cell.html [Content Brief]