SEC14L1 Antibody (YA8762)(PBS only)
(Synonyms: PRELID4A; SEC14L)SEC14L1 Antibody (YA8762) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SEC14L1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
SEC14L1 Antibody (YA8762) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SEC14L1.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
Full length human recombinant protein of human SEC14L1 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SEC14L1 may play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of RIGI, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of RIGI with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters[1][2].
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Subcellular Localization
Cytoplasm,Golgi apparatus
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Expression
Tissue_Specificity: Ubiquitous -
Isoforms & Post-Translational Modification
Q92503 has three isomers: Q92503-1: 81250 Da (predicted); Q92503-2: 81842 Da (predicted); Q92503-3: 77132 Da (predicted).
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Subunit
Interacts with RIGI (via tandem CARD domain); the interaction is direct (PubMed:23843640)
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SwissProt ID
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Synonyms
PRELID4A; SEC14L
Documentation
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