SYT1 Antibody (YA7119)(PBS only)

Cat. No.: HY-P87431A: Data Sheet User Guide for Antibodies
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SYT1 Antibody (YA7119) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYT1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SYT1 Antibody (YA7119) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SYT1.

Host

Mouse

Molecular Weight

Predicted band size: 48kDa;

Species Reactivity

Human, Mouse, Rat, Rabbit

SwissProt ID

P21579

Immunogen

Purified recombinant fragment of SYT1 expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Solution

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003)

Subcellular Localization：Cytoplasmic vesicle, secretory vesicle membrane,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane,Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane,Cytoplasm

Expression：
Tissue_Specificity: Expressed in melanocytes (PubMed:23999003)

Isoforms & Post-Translational Modification：P21579: 422 amino acids, molecular weight 47573 Da.

Subunit：Homotetramer (Probable)

Synonyms

SVP65, SYT, SYT1, Synaptotagmin-1, Synaptotagmin I, p65, SytI

Documentation

User Guide for Antibodies (1077 KB)