TAF15 Antibody (YA2134)(PBS only)

Cat. No.: HY-P82389A: Data Sheet User Guide for Antibodies
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TAF15 Antibody (YA2134) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TAF15.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TAF15 Antibody (YA2134) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TAF15.

Host

Rabbit

Molecular Weight

Predicted band size: 62 kDa;

Observed band size: 77 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q92804

Gene ID

8148 [NCBI]

Immunogen

A synthetic peptide of human TAF15 aa579-592.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3' (PubMed:21256132). Can enter the preinitiation complex together with the RNA polymerase II (Pol II)

Subcellular Localization：Nucleus; Cytoplasm

Expression：
Tissue_specificity:Ubiquitous. Observed in all human tissues

Isoforms & Post-Translational Modification：Q92804 has 2 isomers: Q92804-1: 61830 Da (predicted); Q92804-2: 61558 Da (predicted).
Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity;ADP-ribosylated during genotoxic stress

Subunit：Belongs to the RNA polymerase II (Pol II) transcriptional multiprotein complex, together with the TATA-binding protein (TBP) and other TBP-associated factors (TAF(II)s). Binds SF1

Research Field

Epigenetics and Nuclear Signaling

Synonyms

TAF15; RBP56; TAF2N; TATA-binding protein-associated factor 2N; 68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56

Documentation

User Guide for Antibodies (1077 KB)