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TFPI2 Antibody (YA6979)

(Synonyms: Placental protein 5 antibody; PP5 antibody; REF1 antibody; Retinal pigment epithelium cell factor 1 antibody; TFPI 2 antibody; TFPI-2 antibody; TFPI2 antibody; TFPI2 PEN antibody; TFPI2_HUMAN antibody; Tissue factor pathway inhibitor 2 antibody)
Customer Review

Based on 1 Customer Validation

TFPI2 Antibody (YA6979) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TFPI2.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, IP

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for TFPI2 Antibody (YA6979)
  • TFPI2 Antibody (YA6979) Product Image
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:5000 1:1000 1-2μg/sample

Product Details

Description

TFPI2 Antibody (YA6979) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TFPI2.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 30 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 27 kDa
Immunogen

Recombinant protein within human TFPI2 aa 1-235.

Sensitivity

Endogenous

Purification

Protein A affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for TFPI2 Antibody (YA6979)
    Western blot analysis of extracts from Jurkat (lane 1(20μg)) 、A549 (lane 2(20μg)) 、HeLa (lane 3(20μg)) 、MCF7 (lane 4(20μg)) 、HT-1080 (lane 5(20μg)) and Human kidney cancer (lane 6(40μg)) using TFPI2 Antibody (HY-P87296) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

Background

  • Function

    TFPI2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin

  • Subcellular Localization

    Secreted

  • Expression


    Tissue_Specificity: Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy

  • Isoforms & Post-Translational Modification

    P48307 has two isomers: P48307-1: 26934 Da (predicted); P48307-2: 25796 Da (predicted).

  • Subunit

    Finds in a complex with ABCB1, TFPI2 and PPP2R3C; leading to the dephosphorylation of ABCB1

  • SwissProt ID

    P48307

  • Synonyms

    Placental protein 5 antibody; PP5 antibody; REF1 antibody; Retinal pigment epithelium cell factor 1 antibody; TFPI 2 antibody; TFPI-2 antibody; TFPI2 antibody; TFPI2 PEN antibody; TFPI2_HUMAN antibody; Tissue factor pathway inhibitor 2 antibody

TFPI2 Antibody (YA6979) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from Jurkat (lane 1(20μg)) 、A549 (lane 2(20μg)) 、HeLa (lane 3(20μg)) 、MCF7 (lane 4(20μg)) 、HT-1080 (lane 5(20μg)) and Human kidney cancer (lane 6(40μg)) using TFPI2 Antibody (HY-P87296) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

  • TFPI2 Antibody (YA6979) Product Image
    1/16
  • Experimental Validation Results for TFPI2 Antibody (YA6979)
  • TFPI2 Antibody (YA6979) Product Image
  • Experimental Validation Results for TFPI2 Antibody (YA6979)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from Jurkat (lane 1(20μg)) 、A549 (lane 2(20μg)) 、HeLa (lane 3(20μg)) 、MCF7 (lane 4(20μg)) 、HT-1080 (lane 5(20μg)) and Human kidney cancer (lane 6(40μg)) using TFPI2 Antibody (HY-P87296) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.
  • Experimental Validation Results for TFPI2 Antibody (YA6979)
  • TFPI2 Antibody (YA6979) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from Jurkat (lane 1(20μg)) 、A549 (lane 2(20μg)) 、HeLa (lane 3(20μg)) 、MCF7 (lane 4(20μg)) 、HT-1080 (lane 5(20μg)) and Human kidney cancer (lane 6(40μg)) using TFPI2 Antibody (HY-P87296) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

  • TFPI2 Antibody (YA6979) Product Image WB