Anticancer agent 284
Anticancer agent 284 exhibits cytotoxicity against osteosarcoma cell line (Hos), non-small cell lung cancer cell line (A549), and colon cancer cell line (HCT-116). Anticancer agent 284 can impact the pRIPK3 kinase concentration in the A549 (2.97 pg/mL). Anticancer agent 284 can be used for the study of cancer.
For research use only. We do not sell to patients.
- Formula: C26H25N5O3S
- Molecular Weight:487.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Anticancer agent 284 (Compound 4) cytotoxic against all the tested cell lines, with an IC50 activity order of HCT-116 (7.3 µM) > A549 (20.4 µM) > Hos (39.9 µM)[1].
Anticancer agent 284 slightly inhibis pRIPK3 in A549 cells (2.97 pg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549 human lung cancer cells
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Concentration:20.4 μM (treat with the IC50 concentration of the active compound)
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Incubation Time:24 h
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Result:Impacted the pRIPK3 kinase concentration in the A549 (2.97 pg/mL).
Chemical Information
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Molecular Weight 487.57
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Formula C26H25N5O3S
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SMILES
CC1=CC=C(C=C1)S(=O)(N/N=C(C2=CC=C(C=C2)N/C=C3C(N(N=C/3C)C4=CC=CC=C4)=O)\C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 284 Related Classifications
HY-178937 Related Classifications
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