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Cat. No.: HY-147909

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Anticancer agent 72

Anticancer agent 72 (compound 8c) is a potent inhibitor of K⁺ channel. Anticancer agent 72 induces apoptosis.

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CAS No.: 2460167-51-3
Formule: C₂₀H₁₉N₇O₂
Masse moléculaire:389.41

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Anticancer agent 72 Chemical Structure

CAS No.: 2460167-51-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
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Activité biologique

Description

Anticancer agent 72 (compound 8c) is a potent inhibitor of K⁺ channel. Anticancer agent 72 induces apoptosis^[1].

In Vitro

Anticancer agent 72 (compound 8c) has an inhibitory effects against PC3, MCF-7, HeLa, SKBr3 and A549 cells with IC₅₀ values of 17.58, 5.55, 0.54, 11.13 and 20.40 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 2460167-51-3
Masse moléculaire 389.41
Formule C₂₀H₁₉N₇O₂
SMILES

O=[N+](C1=CC=C(C2=NN=C3N2N=C(N4CCN(C)CC4)C5=C3C=CC=C5)C=C1)[O-]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Romero AH, et al. Anticancer potential of new 3-nitroaryl-6-(N-methyl)piperazin-1,2,4-triazolo[3,4-a]phthalazines targeting voltage-gated K+ channel: Copper-catalyzed one-pot synthesis from 4-chloro-1-phthalazinyl-arylhydrazones. Bioorg Chem. 2020 Aug;101 [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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