Antiparasitic agent-14
Antiparasitic agent-14 is a potent antiparasitic agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote.
For research use only. We do not sell to patients.
- CAS No.: 3046451-98-0
- Formula: C19H20N4OS
- Molecular Weight:352.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Leishmania |
Trypanosoma |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | CC50 |
295.6 μM
Compound: 27
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Cytotoxicity against mouse RAW264.7 cells incubated for 48 hrs by MTT assay
Cytotoxicity against mouse RAW264.7 cells incubated for 48 hrs by MTT assay
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[PMID: 37062170] |
Antiparasitic agent-14 (compound 27) shows cytotoxicity and antiparasitic activity with a CC50 value of 295.6 µM for RAW 264.7 cells, IC50 value of 1.5, 0.89 µM for trypomastigote and amastigote forms of Trypanosoma cruzi (T. cruzi), respectively[1].
Antiparasitic agent-14 shows antiparasitic activity against promastigote and amastigote forms of Leishmania amazonensis (L. amazonensis) with IC50 value of 22.4, 5.70 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3046451-98-0
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Molecular Weight 352.45
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Formula C19H20N4OS
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SMILES
O=C1N(C2=CC=CC=C2)/C(SC1C(C)C)=N\N=C(C3=CC=NC=C3)/C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiparasitic agent-14 Related Classifications
HY-149078 Related Classifications
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