Antitubercular agent-36

Cat. No.: HY-151960: Data Sheet Handling Instructions
FAQs
Technical Support

Antitubercular agent-36 (compound 53) is an antitubercular agent. Antitubercular agent-36 inhibits the growth of Mtb_H37Rv with a MIC₉₀ value of 1.25 μg/mL. Antitubercular agent-36 can be used for the research of tuberculosis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Antitubercular agent-36 화학구조

CAS No. : 2883173-82-6

사이즈		재고
MOQ		Minimum order quantity
50 mg		견적 받기
100 mg		견적 받기
250 mg		견적 받기
Other size		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
THP-1	IC₅₀	> 100 μg/mL Compound: 53	Cytotoxicity against human THP-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human THP-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 36399878]

In Vitro

Antitubercular agent-36 (0-20 μg/mL; 3-4 d) shows inhibitory effect to Mtb_H37Rv with a MIC₉₀ value of 1.25 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

323.35

화학식

C₁₈H₁₇N₃O₃

CAS No.

2883173-82-6

SMILES

CCOC(C1=NOC(C2=NC(NC3=CC=C(C=C3)C)=CC=C2)=C1)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Girardini M, et al. Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114916. [Content Brief]