Antitubercular agent-58
Antitubercular agent-58 is an antitubercular agent with an IC50 of 51 nM against Mycobacterium tuberculosis H37Rv. Antitubercular agent-58 can be used for the research of tuberculosis.
For research use only. We do not sell to patients.
- Formula: C22H22FN3O3
- Molecular Weight:395.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Antitubercular agent-58 (Compound 20j) potently inhibits the growth of Mycobacterium tuberculosis H37Rv whole cells with an IC50 of 51 nM[1].
Antitubercular agent-58 shows high metabolic clearance in rat hepatocytes and moderate metabolic clearance in human liver microsomes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 395.43
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Formula C22H22FN3O3
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SMILES
O=C1C(C(C2=CC=C(N3C[C@@H](C)O[C@@H](C)C3)C=C2)=C1NCC4=NC(F)=CC=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)