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Cat. No.: HY-162766

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Antitumor agent-184

Antitumor agent-184 (compound 12aa) induces cell apoptosis, with the IC₅₀s of 2.35 μM, 7.32 μM and 10.31 μM in B16-F10 cells, 4T1 cells and CT26 cells, respectively.

For research use only. We do not sell to patients.

CAS No.: 3040164-45-9
Formula: C₂₂H₁₆N₄O₂S
Molecular Weight:400.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Antitumor agent-184 Chemical Structure

CAS No.: 3040164-45-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Antitumor agent-184 (compound 12aa) induces cell apoptosis, with the IC₅₀s of 2.35 μM, 7.32 μM and 10.31 μM in B16-F10 cells, 4T1 cells and CT26 cells, respectively^[1].

Chemical Information

CAS No. 3040164-45-9
Molecular Weight 400.45
Formula C₂₂H₁₆N₄O₂S
SMILES

N#CC(C/1=O)=C2N=C(N)C(C3=C(CCCC3)S4)=C4N2C1=C\C(C5=CC=CC=C5)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Irina A Gorbunova, et al. Design and one-pot synthesis of new substituted pyrrolo[1,2-a]thieno[3,2-e]pyrimidine as potential antitumor agents: in vitro and in vivo studies. Bioorg Chem. 2024 Jul:148:107468. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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