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Cat. No.: HY-106443AR

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Arimoclomol maleate (Standard)

Name: Arimoclomol maleate (Standard)
Brand: MedChemExpress
SKU: HY-106443AR
Price: 150.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: BRX-220 (Standard))

Arimoclomol maleate (Standard) is the analytical standard of Arimoclomol maleate (HY-106443A). This product is intended for research and analytical applications. Arimoclomol maleate (BRX-220) is an orally active co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.Arimoclomol maleate can be used for the study of Niemann–Pick disease type C.

For research use only. We do not sell to patients.

Purity : 98%
CAS No.: 289893-26-1
Formula: C₁₈H₂₄ClN₃O₇
Molecular Weight:429.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Arimoclomol maleate (Standard) Chemical Structure

CAS No.: 289893-26-1

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 289893-26-1
Molecular Weight 429.85
Formula C₁₈H₂₄ClN₃O₇
SMILES

Cl/C(C1=C[N+]([O-])=CC=C1)=N\OC[C@H](O)CN2CCCCC2.OC(/C=C\C(O)=O)=O
Synonyms

BRX-220 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Rakonczay Z Jr, et al. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92. [Content Brief]

[2]. Phukan J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Jul;13(7):482-96. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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