EU101
EU101 (NOV1801) is a humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137, with potential immunostimulatory and antineoplastic activities.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Species Reactivity
Human
In Vitro
EU101 can target and bind to CD137 expressed on various leukocyte subsets, enhance CD137-mediated signaling, induce the proliferation of cytotoxic T lymphocytes and cytokine production, and promote cytotoxic T lymphocyte-mediated anti-tumor immune responses. Meanwhile, it can also induce natural killer cell-mediated tumor cell killing and suppress the immunosuppressive activity of regulatory T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Target
TNFRSF9/4-1BB/CD137
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Anwendung
ELISA, FACS, Functional assay
Chemical Information
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SMILES
[EU101]
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Synonyms
NOV1801
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. EU101.
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EU101 Related Classifications
HY-P992044 Related Classifications
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