Ak2 - adenylate kinase 2 Gene

Also Known as Ak-2; D4Ertd220e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11637

Summary

Predicted to enable adenylate kinase activity. Predicted to contribute to nucleobase-containing compound kinase activity. Predicted to be involved in ATP metabolic process and purine nucleotide metabolic process. Predicted to act upstream of or within phosphorylation. Located in sperm mitochondrial sheath. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in reticular dysgenesis. Orthologous to human AK2 (adenylate kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ak2 Products (4)

mRNA Protein Name
NM_001033966.4 NP_001029138.1 adenylate kinase 2, mitochondrial isoform a
NM_016895.4 NP_058591.2 adenylate kinase 2, mitochondrial isoform b
NM_001033966.4 NP_001029138.1 adenylate kinase 2, mitochondrial isoform a
NM_016895.4 NP_058591.2 adenylate kinase 2, mitochondrial isoform b

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence Verweise Source
located in sperm flagellum IDA
IDA: Inferred from direct assay
16790685 MGI
located in sperm mitochondrial sheath IDA
IDA: Inferred from direct assay
16790685 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenylate kinase 2, mitochondrial

  • AK 2

  • ATP-AMP transphosphorylase 2

  • ATP:AMP phosphotransferase

  • adenylate monophosphate kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-133870 Itaconate-alkyne 98.01% Unkown
HY-118674 AK-2-38 Antagonist / Unkown
HY-161512 hAChE/hBACE-1-IN-4 Inhibitor / Unkown
HY-174999 JAK3-IN-18 Inhibitor / Unkown
HY-178936 JAK2-IN-15 Inhibitor / Unkown
HY-RS00506 AK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04243 EIF2AK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174720 Human EIF2AK2 mRNA / Unkown
HY-RS18207 Eif2ak2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18730 Ak2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24684 Eif2ak2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25217 Ak2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ak2 NCBI NCBI:204