Abcd4 - ATP-binding cassette, sub-family D (ALD), member 4 Gene
Also Known as P69r; P70R; Pxmp1l
Species: Mus musculus
Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that the human protein may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. [provided by RefSeq, Jul 2008]
Abcd4 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_008992.2 | NP_033018.2 | lysosomal cobalamin transporter ABCD4 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
lysosomal cobalamin transporter ABCD4 |
|
|