GPN2 - GPN-loop GTPase 2 Gene

Also Known as ATPBD1B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54707

About GPN2

This gene has 5 transcripts (splice variants), 197 orthologues and 2 paralogues. Ubiquitous expression in spleen (RPKM 6.7), duodenum (RPKM 6.2) and 25 other tissues.

Summary

Predicted to enable GTPase activity. [provided by Alliance of Genome Resources, Apr 2022]

GPN2 Products (1)

mRNA Protein Name
NM_018066.4 NP_060536.3 GPN-loop GTPase 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPN2 Protein Structure

ATP_bind_1

ATP_bind_1: Conserved hypothetical ATP binding protein (14 - 260)

  • 0
  • 100
  • 200
  • 310 a.a.
Protein Preferred Names Protein Names

GPN-loop GTPase 2

  • ATP-binding domain 1 family member B

GPN2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
GPN2 Q9H9Y4 GPN1 Homo sapiens Q9HCN4
Y2H Prey Pooling
32296183
Intra
GPN2 Q9H9Y4 GPN1 Homo sapiens Q9HCN4
Anti Tag CoIP
28514442
Intra
GPN2 Q9H9Y4 GPN1 Homo sapiens Q9HCN4
Validated Y2H
32296183
Intra
GPN2 Q9H9Y4 GPN1 Homo sapiens Q9HCN4
Y2H Array
32296183
Intra
GPN2 Q9H9Y4 GPN1 Homo sapiens Q9HCN4
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Syndromic X-Linked Intellectual Disability Lubs Type

  • Lubs X-Linked Mental Retardation Syndrome

  • Mecp2 Duplication Syndrome

  • Mental Retardation, X-Linked, Syndromic, Lubs Type

  • Mental Retardation, X-Linked, With Recurrent Respiratory Infections

  • Mrxsl

  • X-Linked Intellectual Disability-Hypotonia-Recurrent Infections Syndrome

  • Mental Retardation, X-Linked Syndromic, Lubs Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS05646 GPN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GPN2 VGNC VGNC:41387
Mus musculus GPN2 MGD MGI:2140368
Rattus norvegicus GPN2 RGD RGD:1311749
Macaca mulatta GPN2 VGNC VGNC:73010
Bos taurus GPN2 VGNC VGNC:29539
Felis catus GPN2 VGNC VGNC:62669
Others GPN2 NCBI