Alg2 - asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) Gene

Also Known as ALPG2; CDGIi; MNCb-5081; 1110018A23Rik; 1300013N08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56737

Summary

Predicted to enable several functions, including alpha-1,3-mannosyltransferase activity; calcium-dependent protein binding activity; and protein heterodimerization activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process; protein glycosylation in endoplasmic reticulum; and response to calcium ion. Predicted to be located in several cellular components, including actin cytoskeleton; cytosol; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ii and congenital myasthenic syndrome 14. Orthologous to human ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Alg2 Products (2)

mRNA Protein Name
NM_001355496.1 NP_001342425.1 alpha-1,3/1,6-mannosyltransferase ALG2 isoform 2
NM_019998.3 NP_064382.3 alpha-1,3/1,6-mannosyltransferase ALG2 isoform 1
Protein Preferred Names Protein Names

alpha-1,3/1,6-mannosyltransferase ALG2

  • GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

  • GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase

  • GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

  • alpha-1,3-mannosyltransferase ALG2

  • asparagine-linked glycosylation 2 homo

Orthologs Information

Species Symbol Source ID
Homo sapiens Alg2 NCBI NCBI:85365