C1orf116 - chromosome 1 open reading frame 116 Gene

Also Known as SARG

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79098

About C1orf116

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:207,018,522-207,032,756 (from NCBI)

This gene has 2 transcripts (splice variants) and 248 orthologues. Biased expression in lung (RPKM 46.8), esophagus (RPKM 46.0) and 10 other tissues.

Summary

Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

C1orf116 Products (2)

mRNA Protein Name
NM_001083924.2 NP_001077393.1 specifically androgen-regulated gene protein isoform 2
NM_023938.6 NP_076427.2 specifically androgen-regulated gene protein isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
19447967 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15525603 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C1orf116 Protein Structure

SARG

SARG: Specifically androgen-regulated gene protein (33 - 601)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 601 a.a.
Protein Preferred Names Protein Names

specifically androgen-regulated gene protein

  • specifically androgen-regulated protein

C1orf116 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
SARG Q9BW04 HOMER1 Homo sapiens Q86YM7
Y2H Prey Pooling
25416956
Intra
SARG Q9BW04 HOMER1 Homo sapiens Q86YM7
Y2H Array
25416956
Intra
SARG Q9BW04 HOMER3 Homo sapiens Q9NSC5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Fibrosarcomatous Osteosarcoma

  • Fibroblastic Osteosarcoma

  • Fibrosarcomatous Osteogenic Sarcoma
Lymph Node Carcinoma

  • Lymph Node Cancer

  • Lymph Node Neoplasm

  • Neoplasm Of Lymph Node
Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma

  • DMSMFH

  • Bone Dysplasia With Medullary Fibrosarcoma

  • Bdmf

  • Bone Dysplasia With Malignant Fibrous Histiocytoma

  • Hardcastle Syndrome

  • Diaphyseal Medullary Stenosis-Bone Malignancy Syndrome

  • Myopathy, Limb-Girdle, With Bone Fragility

  • Bone Dysplasia-Medullary Fibrosarcoma Syndrome

  • Diaphyseal Medullary Stenosis-Malignant Fibrous Histiocytoma Syndrome

  • Dms-Mfh

  • Limb-Girdle Myopathy With Bone Fragility

  • Stenosis, Medullary, Diaphyseal, With Malignant Fibrous Histiocytoma
Meninges Sarcoma

  • Meningeal Sarcoma

  • Sarcoma Of Meninges

  • Meningothelial Sarcoma

  • Leptomeningeal Sarcoma
Bone Osteosarcoma

  • Osteosarcoma Of Bone

  • Primary Osteosarcoma Of Bone
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01711 C1orf116 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus C1orf116 RGD RGD:1565034
Macaca mulatta C1orf116 VGNC VGNC:70427
Mus musculus C1orf116 MGD MGI:2138143
Bos taurus C1orf116 VGNC VGNC:52641
Others C1orf116 NCBI