BAS00602705
Based on 1 Customer Validation
BAS00602705 is an E-cadherin inhibitor. BAS00602705 exerts its function by blocking the trans-interactions of E-cadherin molecules within junctional complexes, without permanently altering E-cadherin expression levels. BAS00602705 significantly impairs invadopodia formation in pancreatic cancer cells. BAS00602705 can be used for the study of anti-invasive therapeutic strategies in cancers characterized by dysregulated E-cadherin-mediated invadopodia activity, such as pancreatic ductal adenocarcinoma (PDAC).
For research use only. We do not sell to patients.
- Purity: 98.96%
- CAS No.: 317321-89-4
- Formula: C25H22BrN3O3
- Molecular Weight:492.36
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 317321-89-4
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Appearance Solid
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Molecular Weight 492.36
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Formula C25H22BrN3O3
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Color White to off-white
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SMILES
O=C(NC(CC1=CNC2=C1C=CC=C2)C(NC3=CC=C(C=C3)Br)=O)OCC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (203.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0310 mL | 10.1552 mL | 20.3103 mL | 50.7759 mL |
| 5 mM | 0.4062 mL | 2.0310 mL | 4.0621 mL | 10.1552 mL | |
| 10 mM | 0.2031 mL | 1.0155 mL | 2.0310 mL | 5.0776 mL | |
| 15 mM | 0.1354 mL | 0.6770 mL | 1.3540 mL | 3.3851 mL | |
| 20 mM | 0.1016 mL | 0.5078 mL | 1.0155 mL | 2.5388 mL | |
| 25 mM | 0.0812 mL | 0.4062 mL | 0.8124 mL | 2.0310 mL | |
| 30 mM | 0.0677 mL | 0.3385 mL | 0.6770 mL | 1.6925 mL | |
| 40 mM | 0.0508 mL | 0.2539 mL | 0.5078 mL | 1.2694 mL | |
| 50 mM | 0.0406 mL | 0.2031 mL | 0.4062 mL | 1.0155 mL | |
| 60 mM | 0.0339 mL | 0.1693 mL | 0.3385 mL | 0.8463 mL | |
| 80 mM | 0.0254 mL | 0.1269 mL | 0.2539 mL | 0.6347 mL | |
| 100 mM | 0.0203 mL | 0.1016 mL | 0.2031 mL | 0.5078 mL |
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