Avocadyne
Avocadyne is an orally active mitochondrial fatty acid oxidation (FAO) inhibitor. Avocadyne induces leukemia cell death and reverses diet-induced obesity. Avocadyne inhibits fatty acid oxidation activity in leukemia cells. Avocadyne can be used in studies related to leukemia and obesity.
For research use only. We do not sell to patients.
- CAS No.: 129099-93-0
- Formula: C17H32O3
- Molecular Weight:284.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A498 | IC50 |
4.1 μg/mL
Compound: 3
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Cytotoxicity against human A498 cells by MTT assay
Cytotoxicity against human A498 cells by MTT assay
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[PMID: 9644064] |
| A549 | IC50 |
4.8 μg/mL
Compound: 3
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Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
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[PMID: 9644064] |
| HT-29 | IC50 |
8.9 μg/mL
Compound: 3
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Cytotoxicity against human HT-29 cells by MTT assay
Cytotoxicity against human HT-29 cells by MTT assay
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[PMID: 9644064] |
| MCF7 | IC50 |
6.5 μg/mL
Compound: 3
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Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
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[PMID: 9644064] |
| MIA PaCa-2 | IC50 |
>10 μg/mL
Compound: 3
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Cytotoxicity against human MIAPaCa2 cells by MTT assay
Cytotoxicity against human MIAPaCa2 cells by MTT assay
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[PMID: 9644064] |
| PC-3 | IC50 |
0.61 ng/mL
Compound: 3
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Cytotoxicity against human PC3 cells by MTT assay
Cytotoxicity against human PC3 cells by MTT assay
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[PMID: 9644064] |
Avocadyne (72 h) potently reduces the viability of TEX and AML2 leukemia cells, with IC50 values of 3.10 μM and 11.53 μM, respectively[2].
Avocadyne (10 μM; 7-14 days) potently inhibits the clonogenic capacity of AML cells[2].
Avocadyne (10 μM; 3 h) inhibits fatty acid oxidation activity in TEX and AML2 leukemia cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 129099-93-0
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Molecular Weight 284.44
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Formula C17H32O3
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SMILES
C(CCCCCCCCCCC#C)[C@H](C[C@H](CO)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ahmed N, et al.. Bioaccessibility of avocado polyhydroxylated fatty alcohols. Food chemistry. 2025 Jan 15;463(Pt 1):140811. [Content Brief]
[2]. Tcheng M, et al.. Avocado-derived avocadyne is a potent inhibitor of fatty acid oxidation. Journal of food biochemistry. 2022 Mar;46(3):e13895. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Avocadyne Related Classifications
HY-W746606 Related Classifications
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