Benzyl-PEG12-alcohol
Based on 1 Customer Validation
Benzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 96.70%
- CAS No.: 2218463-17-1
- Formula: C31H56O13
- Molecular Weight:636.77
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2218463-17-1
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Appearance Solid
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Molecular Weight 636.77
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Formula C31H56O13
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Color White to off-white
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SMILES
OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC1=CC=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 125 mg/mL (196.30 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5704 mL | 7.8521 mL | 15.7043 mL | 39.2606 mL |
| 5 mM | 0.3141 mL | 1.5704 mL | 3.1409 mL | 7.8521 mL | |
| 10 mM | 0.1570 mL | 0.7852 mL | 1.5704 mL | 3.9261 mL | |
| 15 mM | 0.1047 mL | 0.5235 mL | 1.0470 mL | 2.6174 mL | |
| 20 mM | 0.0785 mL | 0.3926 mL | 0.7852 mL | 1.9630 mL | |
| 25 mM | 0.0628 mL | 0.3141 mL | 0.6282 mL | 1.5704 mL | |
| 30 mM | 0.0523 mL | 0.2617 mL | 0.5235 mL | 1.3087 mL | |
| 40 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9815 mL | |
| 50 mM | 0.0314 mL | 0.1570 mL | 0.3141 mL | 0.7852 mL | |
| 60 mM | 0.0262 mL | 0.1309 mL | 0.2617 mL | 0.6543 mL | |
| 80 mM | 0.0196 mL | 0.0982 mL | 0.1963 mL | 0.4908 mL | |
| 100 mM | 0.0157 mL | 0.0785 mL | 0.1570 mL | 0.3926 mL |