Interferon kappa
Definition:
May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.
References:
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[1]. D W LaFleur, et al. Interferon-kappa, a novel type I interferon expressed in human keratinocytes. J Biol Chem. 2001 Oct 26;276(43):39765-71. [Content Brief]
[2]. Bernardetta Nardelli, et al. Regulatory effect of IFN-kappa, a novel type I IFN, on cytokine production by cells of the innate immune system. J Immunol. 2002 Nov 1;169(9):4822-30. [Content Brief]
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