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Keratoconus

Definition:

Keratoconus (KTCN) is a frequent corneal ectasia characterized by localized corneal thinning and protrusion. Its exact cause is still unknown and is probably multifactorial.

References:

[1]. Elise Héon, et al. VSX1: a gene for posterior polymorphous dystrophy and keratoconus. Hum Mol Genet. 2002 May 1;11(9):1029-36. [Content Brief]

[2]. M Edwards, et al. The genetics of keratoconus. Clin Exp Ophthalmol. 2001 Dec;29(6):345-51. [Content Brief]

[3]. Miguel Romero-Jiménez, et al. Keratoconus: a review. Cont Lens Anterior Eye. 2010 Aug;33(4):157-66; quiz 205. [Content Brief]

[4]. Xiao-Dan Hao, et al. De novo mutations of TUBA3D are associated with keratoconus. Sci Rep. 2017 Oct 19;7(1):13570. [Content Brief]

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