MCR
Definition:
MCR refers in the retrieved literature to a transplantable rat mammary tumor model from which multiple cell lines were established, rather than one uniquely defined cell line; The model and derived cultures were characterized for growth, morphology, hormone receptors, tumorigenicity, and responses to hormonal manipulation, supporting their use in mammary tumor biology and therapy studies[1]. Because the publication describes cell lines from more than one MCR tumor, the unsuffixed input does not identify a specific culture, clone, or repository accession. For database use, retain MCR as a partially resolved model-level term and obtain the exact derived-line designation before assigning donor, phenotype, function, or drug-response data.
Biomedical Dictionary
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