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Monilethrix

Definition:

Monilethrix is a disease of the hair cortex characterized by an unusually deformed hair shaft and alopecia. It has been named for the beaded appearance of affected hairs. Mutations in type II hair follicle-specific keratins lead to monilethrix.

References:

[1]. A Rossi, et al. Monilethrix treated with minoxidil. Int J Immunopathol Pharmacol. 2011 Jan-Mar;24(1):239-42. [Content Brief]

[2]. Jürgen Schweizer, et al. Hair follicle-specific keratins and their diseases. Exp Cell Res. 2007 Jun 10;313(10):2010-20. [Content Brief]

[3]. W H Irwin McLean, et al. Keratin disorders: from gene to therapy. Hum Mol Genet. 2011 Oct 15;20(R2):R189-97. [Content Brief]

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