MT2
Definition:
MT2 is a human Regulatory T-cell transformed cell line derived from Umbilical cord blood. MT2 is immortalized or transformed by Human T-lymphotropic virus 1 (HTLV-1). MT2 is used to investigate cell proliferation, cell migration, cell invasion, cell-cycle control, cellular metabolism, and receptor signaling and trafficking in a controlled cellular system.
References:
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[1]. Fakhari S, et al. MT2-MMP is differentially expressed in multiple myeloma cells and mediates their growth and progression. Cellular signalling. 2022;92:110248. [Content Brief]
[2]. Kinker GS, et al. MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression. Journal of molecular medicine (Berlin, Germany). 2021;99(2):289-301. [Content Brief]
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