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NC-37

Definition:

NC-37 is a human B-cell-derived cancer cell line derived from Bone, jaw, maxilla and associated with EBV-related Burkitt lymphoma and Burkitt lymphoma. NC-37 is immortalized or transformed by Epstein-Barr virus (EBV). NC-37 is used as an in vitro model of EBV-related Burkitt lymphoma and Burkitt lymphoma to investigate host-pathogen interactions and viral infection.

References:

[1]. Rymo L, et al. Analysis of restriction endonuclease fragments of intracellular Epstein-Barr virus DNA and isoenzymes indicate a common origin of the Raji, NC-37, and F-265 human lymphoid cell lines. Virology. 1981;115(1):115-24.

[2]. Bass LR, Hetrick FM. Human lymphoblastoid cells as hosts for parvoviruses H-1 and rat virus. Journal of virology. 1978;25(2):486-90.

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