Spindlin-2B
Definition:
Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors. Exhibits H3K4me3-binding activity.
References:
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[1]. B S Fletcher, et al. Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression. Leukemia. 2002 Aug;16(8):1507-18. [Content Brief]
[2]. Narkhyun Bae, et al. A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1. J Biol Chem. 2017 Dec 22;292(51):20808-20817. [Content Brief]
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