Suppressyn

Definition:

May play a role in trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development. May negatively regulate cell-cell fusion by interacting with SLC1A5, the probable receptor on the cell surface of the fusogenic syncytin-1/ERVW-1.

References:

[1]. Jun Sugimoto, et al. A novel human endogenous retroviral protein inhibits cell-cell fusion. Sci Rep. 2013;3:1462. [Content Brief]

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