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Cat. No.: HY-W668749A

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3BP-3580 TFA

Name: 3BP-3580 TFA
Brand: MedChemExpress
SKU: HY-W668749A
Price: 138.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

3BP-3580 TFA (compound 11) is a conjugate targeting FAP that binds to FAP-positive cells via the FAPI moiety and internalizes, delivering the payload to FAP-expressing cells, thereby inhibiting RA FLS proliferation, migration, and invasion, reducing inflammatory cytokine expression, and suppressing pannus formation. 3BP-3580 TFA can be used for research on rheumatoid arthritis.

For research use only. We do not sell to patients.

Formula: C₃₁H₃₇F₅N₆O₇
Molecular Weight:700.65

Storage:

-20°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

3BP-3580 TFA Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Appearance Solid
Molecular Weight 700.65
Formula C₃₁H₃₇F₅N₆O₇
SMILES

O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCN4CCN(CC4)C(OC(C)(C)C)=O)C=C3)=O.O=C(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang L, et al. Coupled drugs and their preparation methods and their application in the preparation of synovial drugs for the treatment of rheumatoid arthritis. CN116874545A. China. 2023.10.13.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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