3117543-49-1
3117543-49-1
Chemical Structure
JYQ-164
- CAS No.: 3117543-49-1
- Formula:C23H26N6O5S2
- Molecular Weight:530.62
InChIKey: OIDCEUZVEWFKMP-QGZVFWFLSA-N
SMILES: O=C([C@H]1CN(C#N)CC1)NC(S2)=NC3=C2CN(C(C4=CC=CC(S(=O)(N5CCOCC5)=O)=C4)=O)CC3
Biological Activity: JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JYQ-164 | 99.43% | JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research. | ||||||||||||||||||||
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