CCDC90B - coiled-coil domain containing 90B Gene

Also Known as MDS011; MDS025

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 60492

About CCDC90B

This gene has 19 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 14.9), adrenal (RPKM 10.5) and 25 other tissues.

Summary

Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

CCDC90B Products (6)

mRNA Protein Name
NM_001286116.2 NP_001273045.2 coiled-coil domain-containing protein 90B, mitochondrial isoform c
NM_001286117.3 NP_001273046.1 coiled-coil domain-containing protein 90B, mitochondrial isoform c
NM_001286118.3 NP_001273047.1 coiled-coil domain-containing protein 90B, mitochondrial isoform d
NM_001286119.3 NP_001273048.1 coiled-coil domain-containing protein 90B, mitochondrial isoform d
NM_001286120.3 NP_001273049.1 coiled-coil domain-containing protein 90B, mitochondrial isoform e
NM_021825.5 NP_068597.2 coiled-coil domain-containing protein 90B, mitochondrial isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27184846 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC90B Protein Structure

DUF1640

DUF1640: Protein of unknown function (DUF1640) (60 - 254)

  • 0
  • 100
  • 200
  • 254 a.a.
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 90B, mitochondrial

CCDC90B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC90B Q9GZT6 MCUR1 Homo sapiens Q96AQ8
Anti Tag CoIP
33961781
Intra
CCDC90B Q9GZT6 YWHAG Homo sapiens P61981
Y2H Pooling
32814053
Intra
CCDC90B Q9GZT6 YWHAG Homo sapiens P61981
Validated Y2H
32814053
Intra
CCDC90B Q9GZT6 YWHAG Homo sapiens P61981
Y2H Array
32814053
Intra
CCDC90B Q9GZT6 GORASP2 Homo sapiens Q9H8Y8
Y2H Prey Pooling
32296183
Intra
CCDC90B Q9GZT6 GORASP2 Homo sapiens Q9H8Y8
Validated Y2H
32296183
Intra
CCDC90B Q9GZT6 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
32296183
Intra
CCDC90B Q9GZT6 SETDB1 Homo sapiens Q15047-2
Validated Y2H
32814053
Intra
CCDC90B Q9GZT6 SETDB1 Homo sapiens Q15047-2
Y2H Pooling
32814053
Intra
CCDC90B Q9GZT6 SETDB1 Homo sapiens Q15047-2
Y2H Array
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Oculoauricular Syndrome

  • OCACS

  • Schorderet-Munier-Franceschetti Syndrome

  • Microphthalmia, Microcornea, Anterior Segment Dysgenesis, Cataract, Ocular Coloboma, Retinal Pigment Epithelium Abnormalities, Rod-Cone Dystrophy, And Anomalies Of The External Ear

  • Oculoauricular Syndrome, Schorderet Type

  • Oculo-Auricular Syndrome
Osteochondrosis

  • Osteochondritis

  • Apophysitis

  • Epiphysitis

  • Osteochondritis Juvenilis

  • Epiphyseal Necrosis

  • Juvenile Osteochondrosis Of Tibial Tubercle
Epilepsy, Myoclonic Juvenile

  • Juvenile Myoclonic Epilepsy

  • Janz Syndrome

  • Jme

  • Myoclonic Epilepsy, Juvenile, Susceptibility To, 1

  • EJM

  • Myoclonic Epilepsy, Juvenile

  • Petit Mal, Impulsive

  • Myoclonic Epilepsy, Juvenile 1

  • Myoclonic Epilepsy, Juvenile, 1

  • Adolescent Myoclonic Epilepsy

  • Juvenile Myoclonus Epilepsy

  • Juvenile Myoclonic Epilepsy 1

  • EJM1

  • Petit Mal Impulsive

  • Susceptibility To Juvenile Myoclonic Epilepsy 1

  • Myoclonic Epilepsy Juvenile

  • Epilepsy, Myoclonic, Juvenile

  • Myoclonic Epilepsy Of Janz

  • Jme - [Juvenile Myoclonic Epilepsy]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02065 CCDC90B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CCDC90B VGNC VGNC:26931
Mus musculus CCDC90B MGD MGI:1913615
Rattus norvegicus CCDC90B RGD RGD:1308637
Canis familiaris CCDC90B VGNC VGNC:38871
Macaca mulatta CCDC90B VGNC VGNC:70886
Felis catus CCDC90B VGNC VGNC:60527
Others CCDC90B NCBI