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Cat. No.: HY-163089

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Anticancer agent 176

Anticancer agent 176 (Compoint 10α) is an anticancer agent. Anticancer agent 176 exhibits excellent in vitro cytotoxic activity against neuroblastoma with an IC₅₀ value of 6.3 μM.

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Formule: C₃₀H₂₈F₇NO₅
Masse moléculaire:615.54

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Anticancer agent 176 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Anticancer agent 176 (Compoint 10α) is an anticancer agent. Anticancer agent 176 exhibits excellent in vitro cytotoxic activity against neuroblastoma with an IC₅₀ value of 6.3 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Kelly	IC₅₀	6.3 μM Compound: 10alpha	Cytotoxicity against human Kelly cells assessed as inhibition of cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human Kelly cells assessed as inhibition of cell viability incubated for 72 hrs by MTT assay	[PMID: 38086194]
TERT-RPE1	IC₅₀	92.3 μM Compound: 10alpha	Cytotoxicity against human RPE-1 cells assessed as inhibition of cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human RPE-1 cells assessed as inhibition of cell viability incubated for 72 hrs by MTT assay	[PMID: 38086194]

Chemical Information

Masse moléculaire 615.54
Formule C₃₀H₂₈F₇NO₅
SMILES

C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)O[C@H]2O[C@@H]3CO[C@H](O[C@H]3[C@@H]([C@H]2OCC4=CC=C(C=C4)F)N)C5=CC=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Valdivia V, et al. Biological evaluation of carbohydrate-based aprepitant analogs for neuroblastoma treatment. Eur J Med Chem. 2024 Jan 15;264:116021. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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