Ascorutin
Ascorutin (Rutascorbin) is an orally effective antioxidant and anti-inflammatory agent composed of a combination of ascorbic acid and rutin. Ascorutin, based on the synergistic action of ascorbic acid and rutin, comprehensively enhances and regulates local and systemic immune function by reducing oxidative stress, modulating calcium-phosphorus metabolism, and inhibiting the release of inflammatory mediators. Ascorutin can be used in the study of periodontitis.
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- CAS No.: 8067-12-7
- Formule: C33H38O22
- Masse moléculaire:786.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Ascorutin (12.4 mg/kg; 15 days) reduces serum ceruloplasmin activity in rats with experimental periodontitis, decreasing to 382.30 mg/L by day 15[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:white rats (average weight 54 g)[4]
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Dosage:0.25 mg/kg, as part of the TPC
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Administration:i.g.; once daily; 21 days
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Result:Improved the immune and metabolic status of the animals.
- The peripheral blood leukocyte count of the experimental animals significantly decreased by 44.23%.
Increased, with IgG increasing by 7.30%, IgA by 19.45%, and IgM by 17.67%, effectively restoring the body's immune defense capabilities.
Chemical Information
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CAS No. 8067-12-7
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Masse moléculaire 786.64
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Formule C33H38O22
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SMILES
OC[C@@H]([C@]1([H])C(O)=C(C(O1)=O)O)O.O=C(C(O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O)=C(C4=CC(O)=C(C=C4)O)OC5=CC(O)=C6)C5=C6O
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Synonyms
Rutascorbin
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ascorutin Related Classifications
HY-115821 Related Classifications
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